neuromuscular junction

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neuromuscular junction

A motor neuron releases neurotransmitters at the neuromuscular junction to trigger muscle contraction.

Definition
  1. Noun:
    • The site of communication between a motor neuron and a skeletal muscle fiber: A specialized chemical synapse where the terminal end of a motor nerve fiber connects with a muscle fiber, enabling the transmission of signals that cause muscle contraction.
Usage
  • The term is used in biological, medical, and physiological contexts to describe the critical link in the motor system.
  • It is typically used as a countable noun (e.g., , ).
Examples
  • Noun:
    • Acetylcholine is the neurotransmitter released at the neuromuscular junction.
    • Diseases like myasthenia gravis impair signal transmission at the neuromuscular junction.
    • The scientist studied the structure of the neuromuscular junction under an electron microscope.
Advanced Usage
  • "To block the neuromuscular junction": To inhibit or prevent signal transmission at this site, often referring to the action of certain drugs or toxins.
    • Some snake venoms contain toxins that block the neuromuscular junction, causing paralysis.
Variants and Related Words
  • Motor end plate: A synonym often used to refer specifically to the highly folded region of the muscle fiber membrane at the neuromuscular junction.
  • Synapse: A more general term for a junction between two nerve cells or between a nerve cell and another cell type; the neuromuscular junction is a specific type of synapse.
  • Neuromuscular: (Adjective) Pertaining to both nerves and muscles.
    • The doctor ordered a neuromuscular examination.
Synonyms
  • Myoneural junction: A less common but equivalent term.
  • Motor end plate: Emphasizes the specialized post-synaptic component on the muscle fiber.
Related Phrases
  • Neuromuscular transmission: The process of signal transfer across the neuromuscular junction.
    • The drug facilitates neuromuscular transmission.
neuromuscular junction

A motor neuron releases neurotransmitters at the neuromuscular junction to trigger muscle contraction.

Noun
  1. the junction between a nerve fiber and the muscle it supplies

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